Standardized organoid culture is crucial to the construction of organoid sample library and obtaining real and stable experimental results. Using 3D cell cloning screening system to select organoids with better growth status can guarantee more reliable experimental results for drug testing and organoid library construction. The use of this device for organoid selection demonstrates the stability and efficiency of the 3D cell cloning screening system.

This device is a machine vision-based organoid sampling system, including a user interface, a control system communicating with the user interface, a focusable camera communicating with the control system, and a three-axis displacement system communicating with the control system. The three-axis displacement system carries a singlechannel pipette, and the focusable camera captures an image of an organoid and feeds back the captured image to the control system, which transmits the captured image to the user interface. The control system transmits the received organoid images to the user interface